JHDM1D polyclonal (Center), anti-human

JHDM1D polyclonal (Center), anti-human

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In stock
SKU
AC-AP5116c
Catalog Number: AC-AP5116c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26200
Applications: FC, IHC-P, WB
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Background:
JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.

Other Names:
Lysine-specific demethylase 7A, 11411-, JmjC domain-containing histone demethylation protein 1D, Lysine-specific demethylase 7, KDM7A, JHDM1D, KDM7, KIAA1718

Target/Specificity:
This JHDM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the Central region of human JHDM1D.

Antigen Region:
290-316

Antigen Type: Synthetic Peptide

Gene Name: KDM7A
Gene ID: 80853
Primary Accession: Q6ZMT4
NCBI Accession: NP_085150.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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