JIK rabbit polyclonal, anti-human, mouse, rat

Backgroud: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,

Synonyms: TAOK3, DPK, JIK, KDS, MAP3K18, Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhi

Gene Name: TAOK3

Gene ID: 51347

SwissProt ID: Q9H2K8

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.