JMJD2B polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP11950a
Catalog Number: AC-AP11950a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10792
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10792
Applications: WB
Datasheet
Request Information
Background:
KDM4B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20' and only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Other Names:
Lysine-specific demethylase 4B, 11411-, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KDM4B, JHDM3B, JMJD2B, KIAA0876
Target/Specificity:
This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-459 amino acids from the N-terminal region of human JMJD2B.
Antigen Region:
428-459
Antigen Type: Synthetic Peptide
Gene Name: KDM4B
Gene ID: 23030
Primary Accession: O94953
NCBI Accession: NP_055830.1
Other Accession: NP_055830
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
KDM4B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20' and only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Other Names:
Lysine-specific demethylase 4B, 11411-, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KDM4B, JHDM3B, JMJD2B, KIAA0876
Target/Specificity:
This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-459 amino acids from the N-terminal region of human JMJD2B.
Antigen Region:
428-459
Antigen Type: Synthetic Peptide
Gene Name: KDM4B
Gene ID: 23030
Primary Accession: O94953
NCBI Accession: NP_055830.1
Other Accession: NP_055830
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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