JMJD2C polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP11444b
Catalog Number: AC-AP11444b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10796
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10796
Applications: WB, FC
Datasheet
Request Information
Background:
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Other Names:
Lysine-specific demethylase 4C, 11411-, Gene amplified in squamous cell carcinoma 1 protein, GASC-1 protein, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KDM4C, GASC1, JHDM3C, JMJD2C, KIAA0780
Target/Specificity:
This JMJD2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C.
Antigen Region:
1023-1056
Antigen Type: Synthetic Peptide
Gene Name: KDM4C
Gene ID: 23081
Primary Accession: Q9H3R0
NCBI Accession: NP_001140166.1;NP_001140167.1;NP_001140168.1;NP_055876.2
Other Accession: Q8VCD7; NP_001140167.1; NP_001140166.1; NP_001140168.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Other Names:
Lysine-specific demethylase 4C, 11411-, Gene amplified in squamous cell carcinoma 1 protein, GASC-1 protein, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KDM4C, GASC1, JHDM3C, JMJD2C, KIAA0780
Target/Specificity:
This JMJD2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C.
Antigen Region:
1023-1056
Antigen Type: Synthetic Peptide
Gene Name: KDM4C
Gene ID: 23081
Primary Accession: Q9H3R0
NCBI Accession: NP_001140166.1;NP_001140167.1;NP_001140168.1;NP_055876.2
Other Accession: Q8VCD7; NP_001140167.1; NP_001140166.1; NP_001140168.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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