JNK1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
MAPK8(Mitogen-activated protein kinase 8), also known as JNK1, PRKM8, and SAPK1, is an enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this gene is a member of the MAP kinase and JNK family. The International Radiation Hybrid Mapping Consortium mapped the MAPK8 gene to chromosome 10. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. This kinase is also involved in UV radiation-induced apoptosis, which is though to be related to the cytochrome c-mediated cell death pathway.

Description:
Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 8 (MAPK8) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
AI849689 antibody, c Jun N terminal kinase 1 antibody, C-JUN kinase 1 antibody, c-Jun N-terminal kinase 1 antibody, EC 2.7.11.24 antibody, JAK 1A antibody, JAK1A antibody, JNK 1 antibody, JNK 46 antibody, JNK antibody, JNK-46 antibody, JNK1A2 antibody, JNK21B1/2 antibody, MAP kinase 8 antibody, MAPK 8 antibody, MAPK8 antibody, Mitogen activated protein kinase 8 antibody, Mitogen-activated protein kinase 8 antibody, MK08_HUMAN antibody, p54 gamma antibody, PRKM 8 antibody, PRKM8 antibody, Protein kinase JNK1 antibody, Protein kinase, mitogen-activated, 8 antibody, SAPK 1 antibody, SAPK gamma antibody, SAPK1 antibody, Stress activated protein kinase JNK1 antibody, Stress-activated protein kinase 1 antibody, Stress-activated protein kinase JNK1 antibody, Tyrosine protein kinase JAK1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human JNK1(1-15aa MSRSKRDNNFYSVEI), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.