JOSD1 Polyclonal Antibody

Background:
Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.

Research Area: Cell Biology

Synonyms:
JOS1, Josd1, Josephin domain-containing 1, Josephin-1

Immunogen: Fusion protein of human JOSD1

Swissprot: Q15040
Gene Accession: BC015026

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.62 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.