JTB polyclonal, anti-human, rat

Background:
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity.

Synonyms: HJTB, HSPC222, PAR, hJT

Cellular Location: Cytoplasm Membrane Mitochondrion Single-pass type I membrane protein centrosome cytoskeleton microtubule organizing center spindle

Immunogen:
Recombinant protein of human JTB

Gene Symbol: JTB

Gene ID: 10899

Swiss prot: O76095

Calculated MW: 16kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.