JUN Antibody (S63) Blocking Peptide

JUN Antibody (S63) Blocking Peptide

€363.00
In stock
SKU
AC-BP1984d
Catalog Number: AC-BP1984d
Size: 500 µg
Datasheet
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Background:
JUN interacts directly with specific target DNA sequences to regulate gene expression. Jun recognizes the AP-1 consensus sequence TGACTCA, a response element that confers sensitivity to one of the tumor-promoting Phorbol esters, 12-O-tetradecanoyl-phorbol-13-acetate (see also: TRE, TPA response element). Jun itself forms homodimers or heterodimers with junD and junB and also interacts with the oncogene product fos, forming jun-fos heterodimers.

Other Names:
Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1984d was selected from the S63 region of human JUN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: JUN

Gene ID: 3725
Primary Accession: P05412
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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