JUN polyclonal (S63), anti-human

JUN polyclonal (S63), anti-human

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In stock
SKU
AC-AP1984d
Catalog Number: AC-AP1984d
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB11002
Applications: WB
Datasheet

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Background:
JUN interacts directly with specific target DNA sequences to regulate gene expression. Jun recognizes the AP-1 consensus sequence TGACTCA, a response element that confers sensitivity to one of the tumor-promoting Phorbol esters, 12-O-tetradecanoyl-phorbol-13-acetate (see also: TRE, TPA response element). Jun itself forms homodimers or heterodimers with junD and junB and also interacts with the oncogene product fos, forming jun-fos heterodimers.

Other Names:
Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

Target/Specificity:
This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from human JUN.

Antigen Region:
41-70

Antigen Type: Synthetic Peptide

Gene Name: JUN
Gene ID: 3725
Primary Accession: P05412
NCBI Accession: NP_002219.1
Other Accession: P17325; P05627; O77627
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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