Junctophilin 3 Antibody (C-term) Blocking Peptide

Background:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.

Other Names:
Junctophilin-3, JP-3, Junctophilin type 3, Jph3, Jp3

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2715b was selected from the C-term region of human Junctophilin 3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: Jph3

Gene ID: 57340
Primary Accession: Q9ET77
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.