JUP polyclonal, anti-human, mouse, rat

Background:
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

Synonyms: ARVD12, CTNNG, DP3, DPIII, PDGB, PKGB

Cellular Location: Cell junction Cytoplasm Membrane Peripheral membrane protein adherens junction cytoskeleton desmosome

Immunogen:
Recombinant protein of human JUP

Gene Symbol: JUP

Gene ID: 3728

Swiss prot: P14923

Calculated MW: 82kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200, IP 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.