K Cadherin (CDH6) polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP1415b
Catalog Number: AC-AP1415b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14082
Applications: FC, WB, IHC-P
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14082
Applications: FC, WB, IHC-P
Datasheet
Request Information
Background:
CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.
Other Names:
Cadherin-6, Kidney cadherin, K-cadherin, CDH6
Target/Specificity:
This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).
Antigen Region:
665-695
Antigen Type: Synthetic Peptide
Gene Name: CDH6
Gene ID: 1004
Primary Accession: P55285
NCBI Accession: NP_004923.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.
Other Names:
Cadherin-6, Kidney cadherin, K-cadherin, CDH6
Target/Specificity:
This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).
Antigen Region:
665-695
Antigen Type: Synthetic Peptide
Gene Name: CDH6
Gene ID: 1004
Primary Accession: P55285
NCBI Accession: NP_004923.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review