HDAC7 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP70302
Catalog Number: AC-AP51922
Size: 100 µl
Host: Rabbit
Applications: WB, ICC, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, ICC, E
Datasheet
Request Information
Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
Other Names:
HDAC7; HDAC7A; Histone deacetylase 7; HD7; Histone deacetylase 7A; HD7a
Antigen Type: synthetic peptide
Antigen Type: HDAC7
Gene ID: 51564
Primary Accession: Q8WUI4
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
Other Names:
HDAC7; HDAC7A; Histone deacetylase 7; HD7; Histone deacetylase 7A; HD7a
Antigen Type: synthetic peptide
Antigen Type: HDAC7
Gene ID: 51564
Primary Accession: Q8WUI4
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