Kallikrein 1 polyclonal, anti-mouse

Quantity: 100 µg

Background:
KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Description:
Rabbit IgG polyclonal antibody for Kallikrein-1 (KLK1) detection. Tested with WB, IHC-P in Mouse.

Synonyms:
Glandular kallikrein 1 antibody, hK 1 antibody, hK1 antibody, Kallikrein serine protease 1 antibody, Kallikrein-1 antibody, Kidney/pancreas/salivary gland kallikrein antibody, Klk 6 antibody, KLK1 antibody, KLK1_HUMAN antibody, Klk6 antibody, KLKR antibody, Tissue kallikrein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 1(243-261aa YTRVLNFNTWIRETMAEND).A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 1(243-261aa YTRVLNFNTWIRETMAEND).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.