Kallikrein 10 polyclonal, anti-human

Quantity: 100 µg

Background:
KLK10(kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.KLK10 also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The KLK10 gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al.(1997) mapped the PRSSL1 gene to 19q13.3. By genomic sequence analysis, Gan et al.(2000) mapped the KLK10 gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

Description:
Rabbit IgG polyclonal antibody for Kallikrein-10 (KLK10) detection. Tested with WB in Human.

Synonyms:
breast normal epithelial cell associated serine protease antibody, Kallikrein related peptidase 10 antibody, Kallikrein10 antibody, KLK 10 antibody, KLK10 antibody, NES 1 antibody, NES1 antibody, Normal epithelial cell specific 1 antibody, Protease serine like 1 antibody, PRSS L1 antibody, PRSSL 1 antibody, PRSSL1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 10(252-265aa SAQHPAVYTQICKY).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.