Kallikrein 11 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP6330a
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK11, also known as hippostatin, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. KLK11 plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLLK11 arefound in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
Other Names:
Kallikrein-11, hK11, 3421-, Hippostasin, Serine protease 20, Trypsin-like protease, Kallikrein-11 inactive chain 1, Kallikrein-11 inactive chain 2, KLK11, PRSS20, TLSP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6330a was selected from the N-term region of human KLK11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KLK11
Gene ID: 11012
Primary Accession: Q9UBX7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK11, also known as hippostatin, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. KLK11 plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLLK11 arefound in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
Other Names:
Kallikrein-11, hK11, 3421-, Hippostasin, Serine protease 20, Trypsin-like protease, Kallikrein-11 inactive chain 1, Kallikrein-11 inactive chain 2, KLK11, PRSS20, TLSP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6330a was selected from the N-term region of human KLK11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KLK11
Gene ID: 11012
Primary Accession: Q9UBX7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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