Kallikrein-14 polyclonal, anti-human

Protein Family: Enzymes, Peptidases

Pathway and Disease: Signaling Molecules and Interaction

Description:
Kallikrein-14 is a serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. Kallikrein-14 can both activate and inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. Kallikrein-14 functions in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3.

Alternate Names: Kallikrein-14, hK14, Kallikrein-like protein 6, KLK-L6, KLK14, KLKL6

Application Notes: E: 1:10,000-1:50,000; WB: 1:50-1:200

Accession No.: Q9P0G3

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Kallikrein-14.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.