Kallikrein 2 (KLK2) polyclonal (C-term), anti-human
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In stock
SKU
AC-AP6321b
Catalog Number: AC-AP6321b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB06101
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB06101
Applications: WB
Datasheet
Request Information
Background:
Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2; encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.
Other Names:
Kallikrein-2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, KLK2
Target/Specificity:
This Kallikrein 2 (KLK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).
Antigen Region:
166-197
Antigen Type: Synthetic Peptide
Gene Name: KLK2
Gene ID: 3817
Primary Accession: P20151
NCBI Accession: NP_001002231.1;NP_001243009.1;NP_005542.1
Other Accession: NP_005542
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2; encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.
Other Names:
Kallikrein-2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, KLK2
Target/Specificity:
This Kallikrein 2 (KLK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).
Antigen Region:
166-197
Antigen Type: Synthetic Peptide
Gene Name: KLK2
Gene ID: 3817
Primary Accession: P20151
NCBI Accession: NP_001002231.1;NP_001243009.1;NP_005542.1
Other Accession: NP_005542
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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