Kallikrein 5 polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
KLK5(Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme(SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.

Description:
Rabbit IgG polyclonal antibody for Kallikrein related-peptidase 5/Protein Klk5 (KLK5) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
HK5 antibody, Kallikrein 5 antibody, Kallikrein L2 antibody, Kallikrein Like 2 antibody, Kallikrein like protein 2 antibody, Kallikrein related peptidase 5 antibody, Kallikrein-5 antibody, Kallikrein-like protein 2 antibody, Kallikrein5 antibody, KLK 5 antibody, KLK L2 antibody, KLK-L2 antibody, KLK5 antibody, KLK5_HUMAN antibody, KLKL 2 antibody, KLKL2 antibody, SCTE antibody, Stratum Corneum Tryptic Enzyme antibody, UNQ570/PRO1132 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5(278-293aa NLCEFVKWIKDTMNSN), different from the related rat sequence by three amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5(278-293aa NLCEFVKWIKDTMNSN), different from the related rat sequence by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.