Kallistatin polyclonal, anti-human

Quantity: 100 µg

Background:
Serpina 4, also called Kallistatin, PI4 or TISSUE KALLIKREIN INHIBITOR, is a protein that in humans is encoded by the SERPINA4 gene. The serpina4 is a member of the serpin superfamily and represents a major inhibitor of human tissue kallikrein in the circulation. The SERPINA4 gene is localized to 14q32.13. The translated amino acid sequence of serpina4 matches the protein sequence and shares 44 to 46% sequence identity with other serpin family members. Kallistatin is a serine proteinase inhibitor(serpin) and a heparin-binding protein. It is localized in vascular smooth muscle cells and endothelial cells of blood vessels, suggesting that it may be involved in the regulation of vascular function. And serpina4 also plays a role in neointima hyperplasia.

Description:
Rabbit IgG polyclonal antibody for Kallistatin (SERPINA4) detection. Tested with WB, IHC-P in Human.

Synonyms:
KAIN_HUMAN antibody, KAL antibody, Kallikrein binding protein antibody, Kallikrein inhibitor antibody, Kallistatin antibody, KBP antibody, KLST antibody, KST antibody, MGC108582 antibody, Peptidase inhibitor 4 antibody, PI-4 antibody, PI4 antibody, Protease inhibitor 4(kallistatin) antibody, Protease inhibitor 4 antibody, Serine(or cysteine) proteinase inhibitor, clade A(alpha 1 antiproteinase, antitrypsin), member 4 antibody, Serpin A4 antibody, Serpin peptidase inhibitor clade A member 4 antibody, Serpin peptidase inhibitor, clade A(alpha 1 antiproteinase, antitrypsin), member 4 antibody, SERPINA4 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Kallistatin(384-401aa AIKFFSAQTNRHILRFNR).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.