Kallistatin Polyclonal Antibody

Background:
function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,

Alternative Names:
SERPINA4, KST, PI4, Kallistatin, Kallikrein inhibitor, Peptidase inhibitor 4, PI-4, Serpin A4

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 47

GeneID: SERPINA4

Storage: -20°C/1 year

NOTE: For Research Use Only