KANK1 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM8596b
Catalog Number: AC-AM8596b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1773CT634.49.61
Applications: WB, IHC-P
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1773CT634.49.61
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
Other Names:
KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15, Kidney ankyrin repeat-containing protein, KANK1, ANKRD15, KANK, KIAA0172
Target/Specificity:
This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1.
Antigen Type: Synthesized Peptide
Gene Name: KANK1
Gene ID: 23189
Primary Accession: Q14678
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
Other Names:
KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15, Kidney ankyrin repeat-containing protein, KANK1, ANKRD15, KANK, KIAA0172
Target/Specificity:
This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1.
Antigen Type: Synthesized Peptide
Gene Name: KANK1
Gene ID: 23189
Primary Accession: Q14678
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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