KAP1 polyclonal, anti-human, mouse, rat

Background:
TIF1β, for transcriptional intermediary factor 1-beta, also designated KAP1(for KRAB-associated protein 1), TF1β and TRIM28 (for tripartif motif-containing 28), is a member of the tripartif motif family characterized by three zinc-binding domains, a RING finger, B-boxes and a coiled-coil domain. Like TIF1α, TIF1β contains both a Cys/His PHD (plant homeodomain) finger and bromodomain that form a cooperative unit required for transcriptional repression. TIF1β mediates transcriptional control by interaction with the Kruppel-associated box (KRAB) repression domain found in many transcription factors and by binding DNA through its zinc finger. The human TIF1β gene maps to human chromosome 19q13.4 and encodes an 835 amino acid nuclear protein.

Alternative Name:
TIF1-beta, KAP-1, KRIP-1, TRIM28, E3 SUMO protein ligase TRIM28, E3 SUMO-protein ligase TRIM28, FLJ29029, KAP 1, KAP-1, KRAB associated protein 1, KRAB interacting protein 1, KRAB-associated protein 1, KRAB-interacting protein 1, KRIP 1, KRIP-1, KRIP1, Nuclear corepressor KAP 1, Nuclear corepressor KAP-1, RING finger protein 96, RNF96, TF1B, TIF1 beta, TIF1-beta, TIF1B, TIF1B, Transcription intermediary factor 1 beta, Transcription intermediary factor 1-beta, Trim28, Tripartite motif containing 28, tripartite motif containing protein 28, Tripartite motif-containing protein 28,

Application Dilution:
WB:1:2,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: KAP1 polyclonal antibody detects endogenous levels of KAP1 protein.

Immunogen:
recombinant protein

MW: 110 kDa

Swiss-Prot: Q13263(Human) Q62318(Mouse) O08629(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.