KARS polyclonal, anti-human, mouse, rat

Background:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Name:
CMTRIB, DFNB89, KARS1, KARS2, KRS

Application Dilution: WB: 1:500 - 1:2000

Specificity: KARS polyclonal antibody detects endogenous levels of KARS protein.

Immunogen:
Recombinant protein of human KARS

MW: 72kDa

Swis Prot.: Q15046

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.