KARS Polyclonal Antibody

Background:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
CMTRIB, DFNB89, EC 6.1.1.6, KARS 1, KARS 2, KARS, KARS1, KARS2, KIAA0070, KRS, Lysine tRNA ligase, Lysine--tRNA ligase, LysRS, Lysyl-tRNA synthetase, SYK

Immunogen: Recombinant protein of human KARS

Swissprot: Q15046
Gene Accession: BC004132

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-79253/sc-79256/sc-98559