KARS polyclonal (N-term), anti-human

KARS polyclonal (N-term), anti-human

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In stock
SKU
AC-AP11097a
Catalog Number: AC-AP11097a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14918
Applications: WB, FC
Datasheet

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Background:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Other Names:
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS, KARS, KIAA0070

Target/Specificity:
This KARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human KARS.

Antigen Region:
70-98

Antigen Type: Synthetic Peptide

Gene Name: KARS1 (HGNC:6215)
Gene ID: 3735
Primary Accession: Q15046
NCBI Accession: NP_001123561.1;NP_005539.1
Other Accession: NP_005539.1;NP_001123561.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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