KAT3B/p300 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
E1A binding protein p300 also known as EP300 or p300 is a protein that in humans is encoded by the EP300 gene. The EP300 gene is located on the long (q) arm of the human chromosome 22 at position 13.2. This protein regulates the activity of many genes in tissues throughout the body. It plays an essential role in regulating cell growth and division, prompting cells to mature and assume specialized functions (differentiate), and preventing the growth of cancerous tumors. The EP300 protein appears to be critical for normal development before and after birth. It carries out its function by activating transcription. In addition, the protein functions as histone acetyltransferase that regulates transcription via chromatin remodeling, and is important in the processes of cell proliferation and differentiation. EP300 also mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein.

Description:
Rabbit IgG polyclonal antibody for Histone acetyltransferase p300 (EP300) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
CREBBP/EP300 inhibitory protein 1 antibody, Cyclic AMP responsive enhancer binding protein antibody, E1A associated protein p300 antibody, E1A binding protein p300 antibody, E1A-associated protein p300 antibody, EC 2.3.1.48 antibody, EP300 antibody, EP300: E1A binding protein p300 antibody, EP300_HUMAN antibody, Histone acetyltransferase p300 antibody, KAT3B antibody, p300 HAT antibody, RB and P300 binding protein EID 1 antibody, Retinoblastoma protein associated protein antibody, RSTS2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human KAT3B recombinant protein (Position: L2065-H2414). Human KAT3B shares 94% amino acid (aa) sequence identity with mouse KAT3B.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.