KAT6B Polyclonal Antibody

Background:
lysine acetyltransferase 6B(KAT6B) Homo sapiens The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012],

Immunogen: Synthesized peptide derived from human protein . at AA range: 1170-1250

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 228

GeneID: KAT6B KIAA0383 MORF MOZ2 MYST4

Storage: -20°C/1 year

NOTE: For Research Use Only