KChIP1 polyclonal antibody, anti-human, mouse, rat

Background:
KCNIP1 encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The potassium voltage-gated channel interacting protein 1 may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Signal Transduction, Metabolism

Synonyms: KCNIP1, KCHIP1, VABP, Kv channel-interacting protein 1, KChIP1, A-type potassium channel modulatory protein 1, Potassium channel-interacting protein 1, Vesicle APC-binding protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year