KCNA1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Synonyms: EA1, MK1, AEMK, HBK1, HUK1, MBK1, RBK1, KV1.1

Cellular Location: Cytoplasm,Cell membrane

Immunogen:
A synthetic peptide of human KCNA1

Gene Symbol: KCNA1

Gene ID: 3736

Swiss prot: Q09470

Calculated MW: 56 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:15-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.