KCNA2 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8107
Background:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns.Functional KV channels assemble as tetramers consisting of pore-forming α-subunits (KV), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. Differences exist in the patterns of trafficking, biosynthetic processing, and surface expression of the major KV1 subunits (KV1.1, KV1.2, and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
Alternative Name:
Potassium voltage-gated channel subfamily A member 2, , NGK1, Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel HBK5, Voltage-gated potassium channel subunit Kv1.2, KCNA2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: KCNA2 polyclonal antibody detects endogenous levels of KCNA2 protein.
Immunogen:
Recombinant full length Human KCNA2.
MW: ~ 57 kDa
Swis Prot.: P16389
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns.Functional KV channels assemble as tetramers consisting of pore-forming α-subunits (KV), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. Differences exist in the patterns of trafficking, biosynthetic processing, and surface expression of the major KV1 subunits (KV1.1, KV1.2, and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
Alternative Name:
Potassium voltage-gated channel subfamily A member 2, , NGK1, Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel HBK5, Voltage-gated potassium channel subunit Kv1.2, KCNA2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: KCNA2 polyclonal antibody detects endogenous levels of KCNA2 protein.
Immunogen:
Recombinant full length Human KCNA2.
MW: ~ 57 kDa
Swis Prot.: P16389
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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