KCNA2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP14749b
Catalog Number: AC-AP14749b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34951
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34951
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Potassium channels represent the most complex class ofvoltage-gated ion channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, members ofwhich allow nerve cells to efficiently repolarize following anaction potential. The coding region of this gene is intronless, andthe gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Other Names:
Potassium voltage-gated channel subfamily A member 2, NGK1, Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel HBK5, Voltage-gated potassium channel subunit Kv12, KCNA2
Target/Specificity:
This KCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the C-terminal region of human KCNA2.
Antigen Region:
451-479
Antigen Type: Synthetic Peptide
Gene Name: KCNA2
Gene ID: 3737
Primary Accession: P16389
NCBI Accession: NP_001191198.1;NP_004965.1
Other Accession: P63142; Q09081; P63141; NP_004965.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Potassium channels represent the most complex class ofvoltage-gated ion channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, members ofwhich allow nerve cells to efficiently repolarize following anaction potential. The coding region of this gene is intronless, andthe gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Other Names:
Potassium voltage-gated channel subfamily A member 2, NGK1, Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel HBK5, Voltage-gated potassium channel subunit Kv12, KCNA2
Target/Specificity:
This KCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the C-terminal region of human KCNA2.
Antigen Region:
451-479
Antigen Type: Synthetic Peptide
Gene Name: KCNA2
Gene ID: 3737
Primary Accession: P16389
NCBI Accession: NP_001191198.1;NP_004965.1
Other Accession: P63142; Q09081; P63141; NP_004965.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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