KCNA3 polyclonal (Center), anti-human
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In stock
SKU
AC-AP14690c
Catalog Number: AC-AP14690c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34612
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34612
Applications: WB
Datasheet
Request Information
Background:
Potassium channels represent the most complex class ofvoltage-gated ion channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, members ofwhich allow nerve cells to efficiently repolarize following anaction potential. It plays an essential role in T-cellproliferation and activation. This gene appears to be intronlessand it is clustered together with KCNA2 and KCNA10 genes onchromosome 1.
Other Names:
Potassium voltage-gated channel subfamily A member 3, HGK5, HLK3, HPCN3, Voltage-gated K(+) channel HuKIII, Voltage-gated potassium channel subunit Kv13, KCNA3, HGK5
Target/Specificity:
This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3.
Antigen Region:
239-268
Antigen Type: Synthetic Peptide
Gene Name: KCNA3
Gene ID: 3738
Primary Accession: P22001
NCBI Accession: NP_002223.3
Other Accession: P15384; P16390; NP_002223.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Potassium channels represent the most complex class ofvoltage-gated ion channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, members ofwhich allow nerve cells to efficiently repolarize following anaction potential. It plays an essential role in T-cellproliferation and activation. This gene appears to be intronlessand it is clustered together with KCNA2 and KCNA10 genes onchromosome 1.
Other Names:
Potassium voltage-gated channel subfamily A member 3, HGK5, HLK3, HPCN3, Voltage-gated K(+) channel HuKIII, Voltage-gated potassium channel subunit Kv13, KCNA3, HGK5
Target/Specificity:
This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3.
Antigen Region:
239-268
Antigen Type: Synthetic Peptide
Gene Name: KCNA3
Gene ID: 3738
Primary Accession: P22001
NCBI Accession: NP_002223.3
Other Accession: P15384; P16390; NP_002223.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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