KCNA5 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP17043B
Catalog Number: AC-AP17043B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36837
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36837
Applications: WB
Datasheet
Request Information
Background:
Potassium channels represent the most complex class ofvoltage-gated ino channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, the function ofwhich could restore the resting membrane potential of beta cellsafter depolarization and thereby contribute to the regulation ofinsulin secretion. This gene is intronless, and the gene isclustered with genes KCNA1 and KCNA6 on chromosome 12. [provided byRefSeq].
Other Names:
Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv15, KCNA5
Target/Specificity:
This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5.
Antigen Region:
508-536
Antigen Type: Synthetic Peptide
Gene Name: KCNA5
Gene ID: 3741
Primary Accession: P22460
NCBI Accession: NP_002225.2
Other Accession: NP_002225.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Potassium channels represent the most complex class ofvoltage-gated ino channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, the function ofwhich could restore the resting membrane potential of beta cellsafter depolarization and thereby contribute to the regulation ofinsulin secretion. This gene is intronless, and the gene isclustered with genes KCNA1 and KCNA6 on chromosome 12. [provided byRefSeq].
Other Names:
Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv15, KCNA5
Target/Specificity:
This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5.
Antigen Region:
508-536
Antigen Type: Synthetic Peptide
Gene Name: KCNA5
Gene ID: 3741
Primary Accession: P22460
NCBI Accession: NP_002225.2
Other Accession: NP_002225.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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