KCNC1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Potassium voltage-gated channel subfamily C member 1, also known as KV3.1, is a protein that in humans is encoded by the KCNC1 gene. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins, and it is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. This gene is mapped to 11p15.1. KCNC1 channels are prominently expressed in brain, and in retinal ganglion cells. High amounts of KCNC1 current decreased the timing accuracy of action potentials but enabled neurons to follow high-frequency stimuli. KCNC1 channels are important for the high-firing frequency of auditory and fast-spiking GABAergic interneurons, retinal ganglion cells; regulation of action potential duration in presynaptic terminals.

Description:
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily C member 1 (KCNC1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
C230009H10Rik antibody, FLJ41162 antibody, FLJ42249 antibody, FLJ43491 antibody, Kcr2 1 antibody, KShIIIB antibody, Kv3.1 antibody, Kv4 antibody, MGC129855 antibody, NGK2 antibody, Potassium voltage-gated channel subfamily C member 1 antibody, Shaw antibody, Voltage gated potassium channel antibody, Voltage gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv3.1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human KCNC1(494-511aa EILEINRAGRKPLRGMSI), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human KCNC1(494-511aa EILEINRAGRKPLRGMSI), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.