KCND3 polyclonal, anti-human, mouse, rat

Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Synonyms: BRGDA9, KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22

Cellular Location: Cell membrane Cell projection Membrane Multi-pass membrane protein dendrite sarcolemma

Immunogen:
Recombinant protein of human KCND3

Gene Symbol: KCND3

Gene ID: 3752

Swiss prot: Q9UK17

Calculated MW: 73kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.