KCNE3 Polyclonal Antibody

Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.

Research Area: Neuroscience

Synonyms:
Cardiac voltage gated potassium channel accessory subunit, HOKPP, KCNE 3, Minimum potassium ion channel related peptide 2, minK related peptide 2, MiRP 2, MiRP2, Potassium voltage gated channel subfamily E member 3, Potassium voltage gated channel, Isk related family, member 3, Voltage gated K+ channel subunit MIRP2

Immunogen: Fusion protein of human KCNE3

Swissprot: Q9Y6H6
Gene Accession: BC032235

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.02 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.