KCNIP1 Polyclonal Antibody

Background:
Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
A type potassium channel modulatory protein 1, A-type potassium channel modulatory protein 1, KChIP1, KCIP1, Kcnip1, Kv channel interacting protein 1, Kv channel-interacting protein 1, MGC9, MGC95, Potassium channel interacting protein 1, Potassium channel-interacting protein 1, VABP, Vesicle APC binding protein, Vesicle APC-binding protein

Immunogen: Synthetic peptide of human KCNIP1

Swissprot: Q9NZI2
Gene Accession: NP055407

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.68 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.