KCNJ11 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP9209a
Catalog Number: AC-AP9209a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21238
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21238
Applications: FC, WB
Datasheet
Request Information
Background:
ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
Other Names:
ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K(+) channel Kir62, Potassium channel, inwardly rectifying subfamily J member 11, KCNJ11
Target/Specificity:
This KCNJ11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ11.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: KCNJ11
Gene ID: 3767
Primary Accession: Q14654
NCBI Accession: NP_001159762.1
Other Accession: O02822; Q61743
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
Other Names:
ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K(+) channel Kir62, Potassium channel, inwardly rectifying subfamily J member 11, KCNJ11
Target/Specificity:
This KCNJ11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ11.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: KCNJ11
Gene ID: 3767
Primary Accession: Q14654
NCBI Accession: NP_001159762.1
Other Accession: O02822; Q61743
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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