KCNJ2 polyclonal, anti-human, mouse, rat

Background:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Synonyms: ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3

Cellular Location: Lipid-anchor Membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human KCNJ2

Gene Symbol: KCNJ2

Gene ID: 3759

Swiss prot: P63252

Calculated MW: 48kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.