KCNJ2 Polyclonal Antibody

Background:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Research Area: Cancer, Neuroscience

Synonyms:
Cardiac inward rectifier potassium channel, HHBIRK 1, HHBIRK1, HHIRK 1, HHIRK1, HIRK 1, hIRK1, Inward rectifier K, Inward rectifier K(+) channel Kir2.1, Inward rectifier potassium channel 2, inwardly rectifying subfamily J member 2, IRK 1, IRK-1, IRK1, IRK2, KCNJ2, KIR2.1, LQT 7, LQT7, Potassium channel, Potassium channel inwardly rectifying subfamily J member 2, Potassium inwardly rectifying channel J2, Potassium inwardly rectifying channel subfamily J member 2, SQT 3, SQT3

Immunogen: Synthetic peptide of human KCNJ2

Swissprot: P63252
Gene Accession: NP000882

Calculated MW: 48 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.