KCNK18 Polyclonal Antibody

Background:
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura.

Research Area: Cancer, Neuroscience, Signal transduction

Synonyms:
K2p18.1, KCNK18, KCNKI, MGR13, OTTHUMP00000020575, Potassium channel subfamily K member 18, TRESK 2, TRESK, TRESK2, TRIK, TWIK related individual K+ channel, TWIK related individual potassium channel, TWIK related spinal cord K+ channel , TWIK related spinal cord potassium channel, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel

Immunogen: Synthetic peptide of human KCNK18

Swissprot: Q7Z418
Gene Accession: NP862823

Calculated MW: 44 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 2.28 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:70-1:350, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.