KCNK9 (TASK-3) polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.

Research Area: Cell biology

Synonyms: Potassium channel subfamily K member 9 , Acid-sensitive potassium channel protein TASK-3, TWIK-related acid-sensitive K, + channel 3, Two pore potassium channel KT3.2, Two pore K, + channel KT3.2, Potassium channel subfamily K member 9, Acid-sensitive potassium channel protein TASK-3, TWIK-related acid-sensitive K, + channel 3, Two pore potassium channel KT3.2, Two pore K, + channel KT3.2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year