KCNMB4 polyclonal, anti-human, mouse, rat

Background:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

Synonyms: BKbeta4, Hbeta4

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human KCNMB4

Gene Symbol: KCNMB4

Gene ID: 27345

Swiss prot: Q86W47

Calculated MW: 24kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.