KCNQ1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12143a
Background:
This gene encodes a voltage-gated potassium channelrequired for the repolarization phase of the cardiac actionpotential. The gene product can form heteromultimers with two otherpotassium channel proteins, KCNE1 and KCNE3. Mutations in this geneare associated with hereditary long QT syndrome (also known asRomano-Ward syndrome), Jervell and Lange-Nielsen syndrome andfamilial atrial fibrillation. The gene is located in a region ofchromosome 11 that contains a number of contiguous genes, which areabnormally imprinted in cancer and the Beckwith-Wiedemann syndrome.This gene is also imprinted, with preferential expression from thematernal allele in some tissues, excluding cardiac muscle.Alternatively spliced transcripts encoding distinct isoforms havebeen described.
Other Names:
Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv71, KCNQ1, KCNA8, KCNA9, KVLQT1
Gene Name: KCNQ1 (HGNC:6294)
Gene ID: 3784
Primary Accession: P51787
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a voltage-gated potassium channelrequired for the repolarization phase of the cardiac actionpotential. The gene product can form heteromultimers with two otherpotassium channel proteins, KCNE1 and KCNE3. Mutations in this geneare associated with hereditary long QT syndrome (also known asRomano-Ward syndrome), Jervell and Lange-Nielsen syndrome andfamilial atrial fibrillation. The gene is located in a region ofchromosome 11 that contains a number of contiguous genes, which areabnormally imprinted in cancer and the Beckwith-Wiedemann syndrome.This gene is also imprinted, with preferential expression from thematernal allele in some tissues, excluding cardiac muscle.Alternatively spliced transcripts encoding distinct isoforms havebeen described.
Other Names:
Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv71, KCNQ1, KCNA8, KCNA9, KVLQT1
Gene Name: KCNQ1 (HGNC:6294)
Gene ID: 3784
Primary Accession: P51787
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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