KCNQ3 polyclonal (C-term), anti-mouse

KCNQ3 polyclonal (C-term), anti-mouse

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SKU
AC-AP14685b
Catalog Number: AC-AP14685b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34593
Applications: WB
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Background:
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).

Other Names:
Potassium voltage-gated channel subfamily KQT member 3, KQT-like 3, Potassium channel subunit alpha KvLQT3, Voltage-gated potassium channel subunit Kv73, KCNQ3

Target/Specificity:
This KCNQ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-679 amino acids from the C-terminal region of human KCNQ3.

Antigen Region:
651-679

Antigen Type: Synthetic Peptide

Gene Name: KCNQ3 (HGNC:6297)
Gene ID: 3786
Primary Accession: O43525
NCBI Accession: NP_001191753.1;NP_004510.1
Other Accession: NP_004510.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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