KCNQ4 antibody (clone 2H6), anti-human, mouse
€435.00
In stock
SKU
AC-AT2603a
Catalog Number: AC-AT2603a
Size: 100 µg
Isotype: mouse IgG3 Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT2603a-KCNQ4-Antibody-monoclonal-M01">Request Information AC-AT2603a">Request Information
Size: 100 µg
Isotype: mouse IgG3 Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT2603a-KCNQ4-Antibody-monoclonal-M01">Request Information AC-AT2603a">Request Information
Background:
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Potassium voltage-gated channel subfamily KQT member 4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Voltage-gated potassium channel subunit Kv74, KCNQ4
Antigen Type:
Recombinant Protein
Gene Name: KCNQ4
Gene ID: 9132
NCBI Accession: NP_004691.2;NP_751895.1
Primary Accession: P56696
Other Accession: NM_004700
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Potassium voltage-gated channel subfamily KQT member 4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Voltage-gated potassium channel subunit Kv74, KCNQ4
Antigen Type:
Recombinant Protein
Gene Name: KCNQ4
Gene ID: 9132
NCBI Accession: NP_004691.2;NP_751895.1
Primary Accession: P56696
Other Accession: NM_004700
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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