PIK3R6 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP51817
Catalog Number: AC-AP54763
Size: 100 µl
Host: Rabbit
Applications: IHC-P, IHC-F, IF, ICC, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Background:
Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS.
Other Names:
Phosphoinositide 3-kinase regulatory subunit 6, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa, p84 PI3K adapter protein, p84 PIKAP, p87 PI3K adapter protein, p87PIKAP, PIK3R6, C17orf38
Antigen Type: synthetic peptide
Antigen Type: PIK3R6
Gene ID: 146850
Primary Accession: Q5UE93
Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS.
Other Names:
Phosphoinositide 3-kinase regulatory subunit 6, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa, p84 PI3K adapter protein, p84 PIKAP, p87 PI3K adapter protein, p87PIKAP, PIK3R6, C17orf38
Antigen Type: synthetic peptide
Antigen Type: PIK3R6
Gene ID: 146850
Primary Accession: Q5UE93
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