KCTD13 Polyclonal Antibody

Background:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Synonyms:
BACD1, BACURD1, BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, BTB/POZ domain-containing protein KCTD13, FKSG86, hBACURD1, KCTD13, PDIP1, POLDIP 1, POLDIP1, Polymerase delta-interacting protein 1, Potassium channel tetramerisation domain containing 13 , PP6832, TNFAIP1 like polymerase delta interacting protein 1, TNFAIP1-like protein

Immunogen: Fusion protein of human KCTD13

Swissprot: Q8WZ19
Gene Accession: BC036228

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.