KCTD16 Polyclonal Antibody

Background:
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

Synonyms:
BTB/POZ domain containing protein KCTD16, BTB/POZ domain-containing protein KCTD16, DKFZp781A1155, KCD16, KCTD16, KIAA1317, MGC138167, Potassium channel tetramerisation domain containing 16, Potassium channel tetramerization domain containing protein 16, Potassium channel tetramerization domain-containing protein 16, RGD1559856

Immunogen: Fusion protein of human KCTD16

Swissprot: Q68DU8
Gene Accession: BC113435

Calculated MW: 49 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.8 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.